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Growth hormone secretagogue
Ipamorelin
A synthetic pentapeptide investigated for its ability to stimulate growth hormone release.
How it works
Ipamorelin activates the ghrelin receptor (GHS-R1a), a signalling pathway that can trigger growth hormone secretion. This differs from the GHRH-receptor pathway targeted by GHRH analogues.
Research context
It has been explored in preclinical and clinical research, including studies of gastrointestinal function. This does not establish a general therapeutic benefit, and ipamorelin is not an approved medicine.